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human CHRM3 shRNA silencing AAV

Name 
AAV-h-CHRM3-shRNA
Cat No 
shAAV-205201
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CHRM3.

shAAV-205201
AAV-h-CHRM3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CHRM3 (cholinergic receptor muscarinic 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EGBRS; HM3; PBS
Description (Vector)
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue.
Gene ID
1131
Gene Name (Vector)
cholinergic receptor muscarinic 3
Gene Symbol
CHRM3
HGNC ID
HGNC:1952
ORF Size (aa)
1773
ORF Size (bp)
1773 bp
RefSeq ID
NM_000740
RefSeq Synonyms
NM_000740, BC121026,
Species
human
UniGene ID
Hs.7138

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.