human CHN1 shRNA silencing AAV

Name
AAV-h-CHN1-shRNA

Cat No
shAAV-205176

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human CHN1.

shAAV-205176

AAV-h-CHN1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CHN1 (chimerin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ARHGAP2; CHN; DURS2; NC; RHOGAP2

Description (Vector)

CHN1 encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duane's retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene ID

1123

Gene Name (Vector)

chimerin 1

Gene Symbol

CHN1

HGNC ID

HGNC:1943

ORF Size (aa)

1380

ORF Size (bp)

1380 bp

RefSeq ID

NM_001822

RefSeq Synonyms

NM_001822, NM_001206602, NM_001025201, BC011393,

Species

human

UniGene ID

Hs.654534

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.