human CHMP2A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CHMP2A.
shAAV-205162
AAV-h-CHMP2A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CHMP2A (charged multivesicular body protein 2A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BC-2; BC2; CHMP2; VPS2; VPS2A
Description (Vector)
CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 (PubMed 16730941)).(supplied by OMIM, Mar 2008)
Gene ID
27243
Gene Name (Vector)
charged multivesicular body protein 2A
Gene Symbol
CHMP2A
HGNC ID
HGNC:30216
ORF Size (aa)
669
ORF Size (bp)
669 bp
RefSeq ID
NM_014453
RefSeq Synonyms
NM_198426, NM_014453, BC002502,
Species
human
UniGene ID
Hs.12107
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.