human CHCHD3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CHCHD3.
shAAV-205102
AAV-h-CHCHD3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CHCHD3 (coiled-coil-helix-coiled-coil-helix domain containing 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Coiled-coil-helix-coiled-coil-helix domain-containing protein 3; coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial; Mic19; MICOS complex subunit MIC19; MINOS3; mitochondrial inner membrane organizing system 3; PPP1R22; protein phosphatase 1, regulatory subunit 22
Description (eCommerce)
CCoiled-coil-helix-coiled-coil-helix domain-containing protein 3 (CHCHD3) is an inner mitochondrial membrane scaffold protein. Absence of CHCHD3 affects the structural integrity of mitochondrial cristae and leads to reductions in ATP production, cell growth, and oxygen consumption. CHCHD3 is part of the mitochondrial contact site and cristae organizing system (MICOS) [taken from NCBI Entrez Gene (Gene ID: 54927)].
Gene ID
54927
Gene Name (eCommerce)
coiled-coil-helix-coiled-coil-helix domain containing 3
Gene Name (Vector)
coiled-coil-helix-coiled-coil-helix domain containing 3
Gene Symbol
CHCHD3
HGNC ID
HGNC:21906
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
684
ORF Size (bp)
684 bp
Protein Name (eCommerce)
MICOS complex subunit MIC19
RefSeq ID
NM_017812
RefSeq Synonyms
NM_017812, NM_001317178, NM_001317177, BC014839, BC011596,
Research Areas
Kinase/Phosphatase,Mitochondrion,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,signal_transduction,transcription_translation
Species
human
Target Sentence
CCoiled-coil-helix-coiled-coil-helix domain-containing protein 3 (CHCHD3) is an inner mitochondrial membrane scaffold protein. Absence of CHCHD3 affects the structural integrity of mitochondrial cristae and leads to reductions in ATP production, cell growth, and oxygen consumption. CHCHD3 is part of the mitochondrial contact site and cristae organizing system (MICOS) [taken from NCBI Entrez Gene (Gene ID: 54927)].
UniGene ID
Hs.655010
UniProt ID (eCommerce)
Q9NX63
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.