human CHAF1A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CHAF1A.
shAAV-205095
AAV-h-CHAF1A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CHAF1A (chromatin assembly factor 1 subunit A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CAF1; CAF-1; CAF-1 subunit A; CAF1B; CAF1P150; CAF-I 150 kDa subunit; CAF-I p150; chromatin assembly factor 1 subunit A; chromatin assembly factor I (150 kDa); chromatin assembly factor I p150 subunit; CTB-50L17.7; hp150; P150
Description (eCommerce)
Caf1p150 is one of three subunits that make up the chromatin assembly factor I (CAFI). The CAFI subunits include Caf1 (p150; CHAF1A), P50, and p60 (CHAF1B; MIM 601245). The CAFI complex plays an important role in histone octamer assembly during DNA replication. The p150 subunit has been shown to directly interact with histone H3 and H4 as well as the proliferating cell nuclear antigen (PCNA) and is critical to nucleosome assembly during DNA replication.
Description (Vector)
Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B; MIM 601245), and p150 (CHAF1A) subunits that assembles histone octamers onto replicating DNA in vitro (Kaufman et al., 1995 (PubMed 7600578)).(supplied by OMIM, Mar 2008)
Gene ID
10036
Gene Name (eCommerce)
chromatin assembly factor 1 subunit A
Gene Name (Vector)
chromatin assembly factor 1 subunit A
Gene Symbol
CHAF1A
HGNC ID
HGNC:1910
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2871
ORF Size (bp)
2871 bp
Protein Name (eCommerce)
Chromatin assembly factor 1 subunit A
RefSeq ID
NM_005483
RefSeq Synonyms
NM_005483, BC067093,
Research Areas
Cell Cycle,Chromatin Remodeling,DNA Damage/Repair,DNA Replication,Immunology,Protein Folding,Replication,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation,immunology
Species
human
Target Sentence
Caf1p150 is one of three subunits that make up the chromatin assembly factor I (CAFI). The CAFI subunits include Caf1 (p150; CHAF1A), P50, and p60 (CHAF1B; MIM 601245). The CAFI complex plays an important role in histone octamer assembly during DNA replication. The p150 subunit has been shown to directly interact with histone H3 and H4 as well as the proliferating cell nuclear antigen (PCNA) and is critical to nucleosome assembly during DNA replication.
UniGene ID
Hs.79018
UniProt ID (eCommerce)
Q13111
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.