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human EFEMP2 shRNA silencing AAV

Name 
AAV-h-EFEMP2-shRNA
Cat No 
shAAV-205052
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human EFEMP2.

shAAV-205052
AAV-h-EFEMP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EFEMP2 (EGF containing fibulin like extracellular matrix protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ARCL1B; FBLN4; MBP1; UPH1
Description (Vector)
A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. The protein encoded by this gene contains four EGF2 domains and six calcium-binding EGF2 domains. This gene is necessary for elastic fiber formation and connective tissue development. Defects in this gene are cause of an autosomal recessive cutis laxa syndrome. Alternatively spliced transcript variants have been identified for this gene.
Gene ID
30008
Gene Name (Vector)
EGF containing fibulin like extracellular matrix protein 2
Gene Symbol
EFEMP2
HGNC ID
HGNC:3219
ORF Size (aa)
1332
ORF Size (bp)
1332 bp
RefSeq ID
NM_016938
RefSeq Synonyms
NM_016938, BC010456,
Species
human
UniGene ID
Hs.170622

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.