human CFHR1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CFHR1.
shAAV-205045
AAV-h-CFHR1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CFHR1 (complement factor H related 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CFHL; CFHL1; CFHL1P; CFHR1P; FHR1; H36-1; H36-2; HFL1; HFL2
Description (Vector)
CFHR1 encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
Gene ID
3078
Gene Name (Vector)
complement factor H related 1
Gene Symbol
CFHR1
HGNC ID
HGNC:4888
ORF Size (aa)
993
ORF Size (bp)
993 bp
RefSeq ID
NM_002113
RefSeq Synonyms
NM_002113, BC107771, BC016755,
Species
human
UniGene ID
Hs.575869
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.