human CENPH shRNA silencing AAV

Name
AAV-h-CENPH-shRNA

Cat No
shAAV-204956

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human CENPH.

shAAV-204956

AAV-h-CENPH-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CENPH (centromere protein H). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.

Gene ID

64946

Gene Name (Vector)

centromere protein H

Gene Symbol

CENPH

HGNC ID

HGNC:17268

ORF Size (aa)

744

ORF Size (bp)

744 bp

RefSeq ID

NM_022909

RefSeq Synonyms

NM_022909, BC015355, BC012024,

Species

human

UniGene ID

Hs.631967

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.