human CDH16 shRNA silencing AAV

Name
AAV-h-CDH16-shRNA

Cat No
shAAV-204809

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CDH16.

shAAV-204809

AAV-h-CDH16-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CDH16 (cadherin 16). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

CDH16 is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

Gene ID

1014

Gene Name (Vector)

cadherin 16

Gene Symbol

CDH16

HGNC ID

HGNC:1755

ORF Size (aa)

2490

ORF Size (bp)

2490 bp

RefSeq ID

NM_004062

RefSeq Synonyms

NM_004062, NM_001204746, NM_001204745, NM_001204744, BC027912,

Species

human

UniGene ID

Hs.513660

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.