human CD69 shRNA silencing AAV

Name
AAV-h-CD69-shRNA

Cat No
shAAV-204675

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CD69.

shAAV-204675

AAV-h-CD69-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CD69 (CD69 molecule). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Activation inducer molecule; activation inducer molecule (AIM/CD69); AIM; BL-AC/P26; CD antigen CD69; CD69 antigen (p60, early T-cell activation antigen); CLEC2C; C-type lectin domain family 2 member C; C-type lectin domain family 2, member C; EA1; early activation antigen CD69; early lymphocyte activation antigen; early T-cell activation antigen p60; GP32/28; leukocyte surface antigen Leu-23; MLR-3

Description (eCommerce)

CD69 is a member of the calcium dependent lectin superfamily of type II transmembrane receptors. CD69 expression is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets [taken from NCBI Entrez Gene (Gene ID: 969)].

Description (Vector)

CD69 encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets.

Gene ID

969

Gene Name (eCommerce)

CD69 molecule

Gene Name (Vector)

CD69 molecule

Gene Symbol

CD69

HGNC ID

HGNC:1694

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

600

ORF Size (bp)

600 bp

Protein Name (eCommerce)

Early activation antigen CD69

RefSeq ID

NM_001781

RefSeq Synonyms

NM_001781, BC007037,

Research Areas

Interleukin Signaling,Signal Transduction

Research Areas (Faceted)

signal_transduction,immunology

Species

human

Target Sentence

CD69 is a member of the calcium dependent lectin superfamily of type II transmembrane receptors. CD69 expression is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets [taken from NCBI Entrez Gene (Gene ID: 969)].

UniGene ID

Hs.208854

UniProt ID (eCommerce)

Q07108

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.