human CD55 shRNA silencing AAV

Name 
AAV-h-CD55-shRNA
Cat No 
shAAV-204666
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CD55.

shAAV-204666
AAV-h-CD55-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CD55 (CD55 molecule (Cromer blood group)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CR; CROM; DAF; TC
Description (Vector)
CD55 encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Gene ID
1604
Gene Name (Vector)
CD55 molecule (Cromer blood group)
Gene Symbol
CD55
HGNC ID
HGNC:2665
ORF Size (aa)
1146
ORF Size (bp)
1146 bp
RefSeq ID
NM_000574
RefSeq Synonyms
NM_001300904, NM_001300903, NM_001300902, NM_001114752, NM_000574, BC001288,
Species
human
UniGene ID
Hs.126517

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.