human CD40LG shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CD40LG.
shAAV-204654
AAV-h-CD40LG-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CD40LG (CD40 ligand). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD154; CD40L; gp39; hCD40L; HIGM1; IGM; IMD3; T-BAM; TNFSF5; TRAP
Description (Vector)
CD40LG is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
Gene ID
959
Gene Name (Vector)
CD40 ligand
Gene Symbol
CD40LG
HGNC ID
HGNC:11935
ORF Size (aa)
786
ORF Size (bp)
786 bp
RefSeq ID
NM_000074
RefSeq Synonyms
NM_000074, BC074950, BC071754,
Species
human
UniGene ID
Hs.592244
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.