human CD36 shRNA silencing AAV

Name 
AAV-h-CD36-shRNA
Cat No 
shAAV-204641
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CD36.

shAAV-204641
AAV-h-CD36-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CD36 (CD36 molecule). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BDPLT10; CD antigen CD36; CD36 antigen (collagen type I receptor, thrombospondin receptor); CD36 molecule (thrombospondin receptor); CHDS7; cluster determinant 36; FAT; fatty acid translocase; glycoprotein IIIb; GP3B; GP4; GPIIIB; GPIV; leukocyte differentiation antigen CD36; PAS IV; PAS-4; PAS-4 protein; PASIV; Platelet collagen receptor; platelet glycoprotein 4; platelet glycoprotein IV; SCARB3; scavenger receptor class B, member 3; Thrombospondin receptor
Description (eCommerce)
CD36 is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, CD36 has a variety of functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. [taken from NCBI Entrez Gene (Gene ID: 948)].
Description (Vector)
CD36 is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Gene ID
948
Gene Name (eCommerce)
CD36 molecule
Gene Name (Vector)
CD36 molecule
Gene Symbol
CD36
HGNC ID
HGNC:1663
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1419
ORF Size (bp)
1419 bp
Protein Name (eCommerce)
Platelet glycoprotein 4
RefSeq ID
NM_000072
RefSeq Synonyms
NM_001289911, NM_001289909, NM_001289908, NM_001127444, NM_001127443, NM_001001548, NM_001001547, NM_000072, BC008406,
Research Areas
Antigen Processing and Presentation,Apoptosis,Cancer,Cardiovascular,Golgi Apparatus,Immunology,Innate Immunity,MAPK Signaling,Metabolism/Metabolic Process,NF-kB Signaling,Signal Transduction,Toll-like Receptor Signaling
Research Areas (Faceted)
cardiovascular,cancer,signal_transduction,immunology,cell_biology,signal_transduction,metabolism,signal_transduction,immunology
Species
human
Target Sentence
CD36 is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, CD36 has a variety of functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. [taken from NCBI Entrez Gene (Gene ID: 948)].
UniGene ID
Hs.120949
UniProt ID (eCommerce)
P16671

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.