human CD19 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CD19.
shAAV-204588
AAV-h-CD19-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CD19 (CD19 molecule). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
B4;B-lymphocyte antigen CD19;B-lymphocyte surface antigen B4;CD antigen CD19;CVID3;differentiation antigen CD19;T-cell surface antigen Leu-12
Description (eCommerce)
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. CD19 encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulatio [taken from NCBI Entrez Gene (Gene ID: 930)].
Description (Vector)
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
Gene ID
930
Gene Name (eCommerce)
CD19 molecule
Gene Name (Vector)
CD19 molecule
Gene Symbol
CD19
HGNC ID
HGNC:1633
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1671
ORF Size (bp)
1671 bp
Protein Name (eCommerce)
B-lymphocyte antigen CD19
RefSeq ID
NM_001770
RefSeq Synonyms
NM_001770, NM_001178098, BC006338,
Research Areas
B Cell Receptor Signaling,Cancer,EGFR Signaling,EGFR Signaling in Cancer,Fc Receptor Signaling,FGF Signaling,Host-Virus Interactions,Immune cells & tumor markers,Immunology,Immuno-Oncology,Innate Immunity,Neurobiology,NGF Signaling,PDGF Signaling,PI3K/Akt Signaling,PI3K-AKT Signaling in Cancer,SCF-KIT Signaling,Signal Transduction
Research Areas (Faceted)
cancer,immuno_oncology,immunology,infectious_disease,neurobiology,signal_transduction,stem_cell_biology
Species
human
Target Sentence
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. CD19 encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulatio [taken from NCBI Entrez Gene (Gene ID: 930)].
UniGene ID
Hs.652262
UniProt ID (eCommerce)
P15391
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.