human CCR9 shRNA silencing AAV

Name
AAV-h-CCR9-shRNA

Cat No
shAAV-204549

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CCR9.

shAAV-204549

AAV-h-CCR9-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CCR9 (C-C motif chemokine receptor 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CC-CKR-9; CDw199; GPR-9-6; GPR28

Description (Vector)

CCR9 is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

10803

Gene Name (Vector)

C-C motif chemokine receptor 9

Gene Symbol

CCR9

HGNC ID

HGNC:1610

ORF Size (aa)

1110

ORF Size (bp)

1110 bp

RefSeq ID

NM_031200

RefSeq Synonyms

NM_031200, NM_006641, NM_001256369, BC069678,

Species

human

UniGene ID

Hs.225946

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.