human CCBL2 shRNA silencing AAV

Name
AAV-h-CCBL2-shRNA

Cat No
shAAV-204217

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human KYAT3.

shAAV-204217

AAV-h-CCBL2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KYAT3 (kynurenine aminotransferase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CCBL2; KAT3; KATIII

Description (Vector)

CCBL2 encodes an aminotransferase that transaminates kynurenine to form kynurenic acid. Kynurenic acid is a metabolite of tryptophan. Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene. CCBL2 shares 5' exon structure with the RNA binding motif protein, X-linked-like 1 locus on chromosome 1, but the coding sequences are non-overlapping.

Gene ID

56267

Gene Name (Vector)

kynurenine aminotransferase 3

Gene Symbol

KYAT3

HGNC ID

HGNC:33238

ORF Size (aa)

873

ORF Size (bp)

873 bp

RefSeq ID

NM_001008662

RefSeq Synonyms

NM_001008662, NM_001008661, BC012942, BC000819,

Species

human

UniGene ID

Hs.481898

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.