human CBR3 shRNA silencing AAV

Name
AAV-h-CBR3-shRNA

Cat No
shAAV-204177

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human CBR3.

shAAV-204177

AAV-h-CBR3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CBR3 (carbonyl reductase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

hCBR3; HEL-S-25; SDR21C2

Description (Vector)

Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.

Gene ID

874

Gene Name (Vector)

carbonyl reductase 3

Gene Symbol

CBR3

HGNC ID

HGNC:1549

ORF Size (aa)

834

ORF Size (bp)

834 bp

RefSeq ID

NM_001236

RefSeq Synonyms

NM_001236, BC002812,

Species

human

UniGene ID

Hs.154510

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.