human CAMK2B shRNA silencing AAV

Name
AAV-h-CAMK2B-shRNA

Cat No
shAAV-203997

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human CAMK2B.

shAAV-203997

AAV-h-CAMK2B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CAMK2B (calcium/calmodulin dependent protein kinase II beta). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CAM2; CAMK2; CAMKB

Description (Vector)

The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene.

Gene ID

816

Gene Name (Vector)

calcium/calmodulin dependent protein kinase II beta

Gene Symbol

CAMK2B

HGNC ID

HGNC:1461

ORF Size (aa)

1512

ORF Size (bp)

1512 bp

RefSeq ID

NM_001220

RefSeq Synonyms

NM_172084, NM_172083, NM_172082, NM_172081, NM_172080, NM_172079, NM_172078, NM_001293170, NM_001220, BC019070,

Species

human

UniGene ID

Hs.351887

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.