human CALR3 shRNA silencing AAV

Name
AAV-h-CALR3-shRNA

Cat No
shAAV-203989

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CALR3.

shAAV-203989

AAV-h-CALR3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CALR3 (calreticulin 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CMH19; CRT2; CT93

Description (Vector)

CALR3 belongs to the calreticulin family, members of which are calcium-binding chaperones localized mainly in the endoplasmic reticulum. This protein is also localized to the endoplasmic reticulum lumen, however, its capacity for calcium-binding may be absent or much lower than other family members. This gene is specifically expressed in the testis, and may be required for sperm fertility. Mutation in this gene has been associated with familial hypertrophic cardiomyopathy.

Gene ID

125972

Gene Name (Vector)

calreticulin 3

Gene Symbol

CALR3

HGNC ID

HGNC:20407

ORF Size (aa)

1155

ORF Size (bp)

1155 bp

RefSeq ID

NM_145046

RefSeq Synonyms

NM_145046, BC014595,

Species

human

UniGene ID

Hs.304020

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.