human CA1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CA1.
shAAV-203863
AAV-h-CA1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CA1 (carbonic anhydrase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CA-I; CAB; Car1; HEL-S-11
Description (Vector)
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Variants of this gene have been described in some populations. Multiple alternatively spliced variants, encoding the same protein, have been identified. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature.
Gene ID
759
Gene Name (Vector)
carbonic anhydrase 1
Gene Symbol
CA1
HGNC ID
HGNC:1368
ORF Size (aa)
786
ORF Size (bp)
786 bp
RefSeq ID
NM_001738
RefSeq Synonyms
NM_001738, NM_001291968, NM_001291967, NM_001164830, NM_001128831, NM_001128830, NM_001128829, BC027890,
Species
human
UniGene ID
Hs.23118
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.