human C3 shRNA silencing AAV

Name 
AAV-h-C3-shRNA
Cat No 
shAAV-203359
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human C3.

shAAV-203359
AAV-h-C3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human C3 (complement C3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AHUS5; ARMD9; ASP; C3a; C3b; CPAMD1; HEL-S-62p
Description (Vector)
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection.
Gene ID
718
Gene Name (Vector)
complement C3
Gene Symbol
C3
HGNC ID
HGNC:1318
ORF Size (aa)
4992
ORF Size (bp)
4992 bp
RefSeq ID
NM_000064
RefSeq Synonyms
NM_000064, BC150200, BC150179,
Species
human
UniGene ID
Hs.529053

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.