human C2ORF30 shRNA silencing AAV

Cat. No: shAAV-203300

Availability: 4-5 weeks

Name: AAV-h-C2ORF30-shRNA

This is an AAV expressing shRNA for silencing of Human ERLEC1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ERLEC1
Gene Name: endoplasmic reticulum lectin 1
Gene ID: 27248
Gene Synonyms: C2orf30; CIM; CL24936; CL25084; HEL117; XTP3-B; XTP3TPB
ORF Size: 1290 bp
RefSeq#: NM_015701
Gene Description: ERLEC1 encodes a resident endoplasmic reticulum (ER) protein that functions in N-glycan recognition. This protein is thought to be involved in ER-associated degradation via its interaction with the membrane-associated ubiquitin ligase complex. It also functions as a regulator of multiple cellular stress-response pathways in a manner that promotes metastatic cell survival. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 21.
UniGene ID: Hs.713845
HGNC ID: HGNC:25222