human C1QC shRNA silencing AAV

Name
AAV-h-C1QC-shRNA

Cat No
shAAV-203136

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human C1QC.

shAAV-203136

AAV-h-C1QC-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human C1QC (complement C1q C chain). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C1Q-C; C1QG

Description (Vector)

C1QC encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. C1QC encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene.

Gene ID

714

Gene Name (Vector)

complement C1q C chain

Gene Symbol

C1QC

HGNC ID

HGNC:1245

ORF Size (aa)

738

ORF Size (bp)

738 bp

RefSeq ID

NM_172369

RefSeq Synonyms

NM_172369, NM_001347620, NM_001347619, NM_001114101, BC009016,

Species

human

UniGene ID

Hs.467753

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.