human C1ORF71 shRNA silencing AAV

Name 
AAV-h-C1ORF71-shRNA
Cat No 
shAAV-203106
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CNST.

shAAV-203106
AAV-h-C1ORF71-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CNST (consortin, connexin sorting protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C1orf71; PPP1R64
Description (Vector)
Targeting of numerous transmembrane proteins to the cell surface is thought to depend on their recognition by cargo receptors that interact with the adaptor machinery for anterograde traffic at the distal end of the Golgi complex. Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins, the building blocks of gap junctions, and acts as a trans-Golgi network (TGN) receptor involved in connexin targeting to the plasma membrane and recycling from the cell surface (del Castillo et al., 2010 (PubMed 19864490)).(supplied by OMIM, Jun 2010)
Gene ID
163882
Gene Name (Vector)
consortin, connexin sorting protein
Gene Symbol
CNST
HGNC ID
HGNC:26486
ORF Size (aa)
1851
ORF Size (bp)
1851 bp
RefSeq ID
NM_152609
RefSeq Synonyms
NM_152609, NM_001139459, BC010228,
Species
human
UniGene ID
Hs.368353

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.