human C1GALT1C1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human C1GALT1C1.
shAAV-202967
AAV-h-C1GALT1C1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human C1GALT1C1 (C1GALT1 specific chaperone 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C1GALT2; C38H2-L1; COSMC; HSPC067; MST143; TNPS
Description (Vector)
C1GALT1C1 encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. C1GALT1C1 product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.
Gene ID
29071
Gene Name (Vector)
C1GALT1 specific chaperone 1
Gene Symbol
C1GALT1C1
HGNC ID
HGNC:24338
ORF Size (aa)
957
ORF Size (bp)
957 bp
RefSeq ID
NM_152692
RefSeq Synonyms
NM_152692, NM_001011551, BC050441, BC011930,
Species
human
UniGene ID
Hs.643920
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.