human C1D shRNA silencing AAV

Name
AAV-h-C1D-shRNA

Cat No
shAAV-202963

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human C1D.

shAAV-202963

AAV-h-C1D-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human C1D (C1D nuclear receptor corepressor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

hC1D; LRP1; Rrp47; SUN-CoR; SUNCOR

Description (Vector)

C1D is a DNA binding and apoptosis-inducing protein and is localized in the nucleus. It is also a Rac3-interacting protein which acts as a corepressor for the thyroid hormone receptor. This protein is thought to regulate TRAX/Translin complex formation. Alternate splicing results in multiple transcript variants that encode the same protein. Multiple pseudogenes of this gene are found on chromosome 10.

Gene ID

10438

Gene Name (Vector)

C1D nuclear receptor corepressor

Gene Symbol

C1D

HGNC ID

HGNC:29911

ORF Size (aa)

426

ORF Size (bp)

426 bp

RefSeq ID

NM_006333

RefSeq Synonyms

NM_173177, NM_006333, NM_001190265, NM_001190263, BC016284, BC009589, BC009584, BC005235,

Species

human

UniGene ID

Hs.602900

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.