human C19ORF61 shRNA silencing AAV

Name 
AAV-h-C19ORF61-shRNA
Cat No 
shAAV-202945
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SMG9.

shAAV-202945
AAV-h-C19ORF61-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SMG9 (SMG9, nonsense mediated mRNA decay factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C19orf61; F17127_1; HBMS; protein SMG9; Protein SMG-9; protein smg-9 homolog
Description (eCommerce)
SMG9 is a subunit of the SMG-1 complex. SMG-1 and Upf1 are part of a surveillance complex that participates in nonsense-mediated mRNA decay (NMD) to degrade mRNAs containing premature translation initiation codons (PTCs).
Gene ID
56006
Gene Name (eCommerce)
SMG9, nonsense mediated mRNA decay factor
Gene Name (Vector)
SMG9, nonsense mediated mRNA decay factor
Gene Symbol
SMG9
HGNC ID
HGNC:25763
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1563
ORF Size (bp)
1563 bp
Protein Name (eCommerce)
Protein SMG9
RefSeq ID
NM_019108
RefSeq Synonyms
NM_019108, BC008869,
Research Areas
Gene Expression,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
SMG9 is a subunit of the SMG-1 complex. SMG-1 and Upf1 are part of a surveillance complex that participates in nonsense-mediated mRNA decay (NMD) to degrade mRNAs containing premature translation initiation codons (PTCs).
UniGene ID
Hs.466875
UniProt ID (eCommerce)
Q9H0W8

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.