human C19ORF56 shRNA silencing AAV

Name
AAV-h-C19ORF56-shRNA

Cat No
shAAV-202939

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human WDR83.

shAAV-202939

AAV-h-C19ORF56-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human WDR83 (WD repeat domain 83). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MORG1

Description (Vector)

WDR83 encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants.

Gene ID

84292

Gene Name (Vector)

WD repeat domain 83

Gene Symbol

WDR83

HGNC ID

HGNC:32672

ORF Size (aa)

948

RefSeq ID

NM_032332

RefSeq Synonyms

NM_032332, NM_001099737, BC005870,

Species

human

UniGene ID

Hs.657204

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.