human C17ORF71 shRNA silencing AAV

Name 
AAV-h-C17ORF71-shRNA
Cat No 
shAAV-202838
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SMG8.

shAAV-202838
AAV-h-C17ORF71-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SMG8 (SMG8, nonsense mediated mRNA decay factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
amplified in breast cancer gene 2 protein; C17orf71; protein SMG8; protein smg-8 homolog; smg-8 homolog, nonsense mediated mRNA decay factor
Description (eCommerce)
ABC2 (amplified in breast cancer 2 gene) has been identified as a gene amplified and overexpressed in breast cancer. The specific function of ABC2 has not been reported.
Gene ID
55181
Gene Name (eCommerce)
SMG8, nonsense mediated mRNA decay factor
Gene Name (Vector)
SMG8, nonsense mediated mRNA decay factor
Gene Symbol
SMG8
HGNC ID
HGNC:25551
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1929
ORF Size (bp)
1929 bp
Protein Name (eCommerce)
Protein SMG8
RefSeq ID
NM_018149
RefSeq Synonyms
NM_018149, BC020957,
Research Areas
Gene Expression,RNA Processing,Signal Transduction
Research Areas (Faceted)
cell_biology,genetics,signal_transduction,transcription_translation
Species
human
Target Sentence
ABC2 (amplified in breast cancer 2 gene) has been identified as a gene amplified and overexpressed in breast cancer. The specific function of ABC2 has not been reported.
UniGene ID
Hs.7296
UniProt ID (eCommerce)
Q8ND04

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.