human C12ORF65 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human C12orf65.
shAAV-202579
AAV-h-C12ORF65-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human C12orf65 (chromosome 12 open reading frame 65). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
COXPD7; SPG55
Description (Vector)
This nuclear gene encodes a mitochondrial matrix protein that appears to contribute to peptide chain termination in the mitochondrial translation machinery. Two different 1 bp deletions (resulting in the same premature stop codon)result in decreased mitochondrial translation, decreased levels of oxidative phosphorylation complexes and encepthalomyopathy. Alternative splicing results in multiple transcript variants.
Gene ID
91574
Gene Name (Vector)
chromosome 12 open reading frame 65
Gene Symbol
C12orf65
HGNC ID
HGNC:26784
ORF Size (aa)
360
RefSeq ID
NM_152269
RefSeq Synonyms
NM_152269, NM_001194995, NM_001143905, BC062329, BC020885, BC018145,
Species
human
UniGene ID
Hs.319128
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.