human C11ORF31 shRNA silencing AAV

Name
AAV-h-C11ORF31-shRNA

Cat No
shAAV-202465

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SELENOH.

shAAV-202465

AAV-h-C11ORF31-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SELENOH (selenoprotein H). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C11orf31; C17orf10; SELH

Description (Vector)

C11orf31 encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. The exact function of this gene is not known, however, selenoproteins are thought to be responsible for most biomedical effects of dietary selenium.

Gene ID

280636

Gene Name (Vector)

selenoprotein H

Gene Symbol

SELENOH

HGNC ID

HGNC:18251

ORF Size (aa)

369

ORF Size (bp)

369 bp

RefSeq ID

NM_170746

RefSeq Synonyms

NM_170746, NM_001321335, BC021122,

Species

human

UniGene ID

Hs.655373

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.