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human BTAF1 shRNA silencing AAV

Name 
AAV-h-BTAF1-shRNA
Cat No 
shAAV-202305
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human BTAF1.

shAAV-202305
AAV-h-BTAF1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BTAF1 (B-TFIID TATA-box binding protein associated factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ATP-dependent helicase BTAF1; BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae); B-TFIID transcription factor-associated 170 kDa subunit; MOT1; Mot1 homolog; TAF(II)170; TAF172; TAF-172; TAFII170; TATA-binding protein-associated factor 172; TBP-associated factor 172
Description (eCommerce)
BTAF1 is a member of the SNF2-like family of ATPases that associates with the TATA-binding protein (TBP) and TAFII170 (TAF172) to form the B-TF-IID complex. As part of the general transcription machinery, BTAF1 acts as a regulator of TBP and RNA polymerase II transcription.
Description (Vector)
BTAF1 encodes a TAF (TATA box-binding protein-associated factor), which associates with TBP (TATA box-binding protein) to form the B-TFIID complex that is required for transcription initiation of genes by RNA polymerase II. This TAF has DNA-dependent ATPase activity, which drives the dissociation of TBP from DNA, freeing the TBP to associate with other TATA boxes or TATA-less promoters.
Gene ID
9044
Gene Name (eCommerce)
B-TFIID TATA-box binding protein associated factor 1
Gene Name (Vector)
B-TFIID TATA-box binding protein associated factor 1
Gene Symbol
BTAF1
HGNC ID
HGNC:17307
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
5550
ORF Size (bp)
5550 bp
Protein Name (eCommerce)
TATA-binding protein-associated factor 172
RefSeq ID
NM_003972
RefSeq Synonyms
NM_003972, BC112201,
Research Areas
Helicase Activity,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
BTAF1 is a member of the SNF2-like family of ATPases that associates with the TATA-binding protein (TBP) and TAFII170 (TAF172) to form the B-TF-IID complex. As part of the general transcription machinery, BTAF1 acts as a regulator of TBP and RNA polymerase II transcription.
UniGene ID
Hs.500526
UniProt ID (eCommerce)
O14981

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.