human BMP5 shRNA silencing AAV

Name
AAV-h-BMP5-shRNA

Cat No
shAAV-202198

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human BMP5.

shAAV-202198

AAV-h-BMP5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BMP5 (bone morphogenetic protein 5). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

BMP5 encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. BMP5 is differentially regulated during the formation of various tumors.

Gene ID

653

Gene Name (Vector)

bone morphogenetic protein 5

Gene Symbol

BMP5

HGNC ID

HGNC:1072

ORF Size (aa)

1365

ORF Size (bp)

1365 bp

RefSeq ID

NM_021073

RefSeq Synonyms

NM_021073, NM_001329756, NM_001329754, BC027958,

Species

human

UniGene ID

Hs.296648

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.