human BLOC1S2 shRNA silencing AAV

Name 
AAV-h-BLOC1S2-shRNA
Cat No 
shAAV-202169
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human BLOC1S2.

shAAV-202169
AAV-h-BLOC1S2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BLOC1S2 (biogenesis of lysosomal organelles complex 1 subunit 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BLOS2; BORCS2; CEAP; CEAP11
Description (Vector)
BLOC1S2 encodes a protein with multiple functions. The encoded protein has been found in association with the centrosome, shown to co-localize with gamma-tubulin, and also found to be one of the proteins in the BLOC-1 complex which functions in the formation of lysosome-related organelles. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants.
Gene ID
282991
Gene Name (Vector)
biogenesis of lysosomal organelles complex 1 subunit 2
Gene Symbol
BLOC1S2
HGNC ID
HGNC:20984
ORF Size (aa)
300
ORF Size (bp)
300 bp
RefSeq ID
NM_001001342
RefSeq Synonyms
NM_173809, NM_001282439, NM_001282438, NM_001282437, NM_001282436, NM_001001342, BC020494,
Species
human
UniGene ID
Hs.34906

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.