human BDKRB1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human BDKRB1.
shAAV-202082
AAV-h-BDKRB1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human BDKRB1 (bradykinin receptor B1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
B1BKR; B1R; BDKRB2; BKB1R; BKR1; BRADYB1
Description (Vector)
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene.
Gene ID
623
Gene Name (Vector)
bradykinin receptor B1
Gene Symbol
BDKRB1
HGNC ID
HGNC:1029
ORF Size (aa)
1062
ORF Size (bp)
1062 bp
RefSeq ID
NM_000710
RefSeq Synonyms
NM_000710, BC034705,
Species
human
UniGene ID
Hs.525572
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.