human BAZ1A shRNA silencing AAV

Name 
AAV-h-BAZ1A-shRNA
Cat No 
shAAV-201987
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human BAZ1A.

shAAV-201987
AAV-h-BAZ1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BAZ1A (bromodomain adjacent to zinc finger domain 1A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ACF1; ATP-dependent chromatin remodeling protein; ATP-dependent chromatin-remodeling protein; ATP-utilizing chromatin assembly and remodeling factor 1; bromodomain adjacent to zinc finger domain protein 1A; CHRAC subunit ACF1; hACF1; hWALp1; WALp1; WCRF180; williams syndrome transcription factor-related chromatin-remodeling factor 180
Description (eCommerce)
ACF1/BAZ1A is a subunit of the ACF chromatin-remodeling complex and the ISWI CHRAC remodeling complex. In the ACF complex, ACF1/BAZ1A functions to influence the nucleosome remodeling activity of the SNF2h ATPase. As part of the CHRAC complex, ACF1/BAZ1A may function to target CHRAC to heterochromatin. ACF1 has also been shown to interact with the nuclear receptor corepressor protein (N-CoR) to facilitate the repression of transcription by unliganded nuclear receptors.
Description (Vector)
The BAZ1A gene encodes the accessory subunit of the ATP-dependent chromatin assembly factor (ACF), a member of the ISWI ('imitation switch') family of chromatin remodeling complexes (summarized by Racki et al., 2009 (PubMed 20033039)).(supplied by OMIM, Apr 2010)
Gene ID
11177
Gene Name (eCommerce)
bromodomain adjacent to zinc finger domain 1A
Gene Name (Vector)
bromodomain adjacent to zinc finger domain 1A
Gene Symbol
BAZ1A
HGNC ID
HGNC:960
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4668
ORF Size (bp)
4668 bp
Protein Name (eCommerce)
Bromodomain adjacent to zinc finger domain protein 1A
RefSeq ID
NM_013448
RefSeq Synonyms
NM_182648, NM_013448, BC156491,
Research Areas
Chromatin Remodeling,DNA Replication,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
ACF1/BAZ1A is a subunit of the ACF chromatin-remodeling complex and the ISWI CHRAC remodeling complex. In the ACF complex, ACF1/BAZ1A functions to influence the nucleosome remodeling activity of the SNF2h ATPase. As part of the CHRAC complex, ACF1/BAZ1A may function to target CHRAC to heterochromatin. ACF1 has also been shown to interact with the nuclear receptor corepressor protein (N-CoR) to facilitate the repression of transcription by unliganded nuclear receptors.
UniGene ID
Hs.509140
UniProt ID (eCommerce)
Q9NRL2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.