human BAMBI shRNA silencing AAV

Cat. No: shAAV-201955

Availability: 4-5 weeks

Name: AAV-h-BAMBI-shRNA

This is an AAV expressing shRNA for silencing of Human BAMBI.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: BAMBI
Gene Name: BMP and activin membrane bound inhibitor
Gene ID: 25805
Gene Synonyms: NMA
ORF Size: 783 bp
RefSeq#: NM_012342
Gene Description: BAMBI encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis.
UniGene ID: Hs.533336
HGNC ID: HGNC:30251