human BAMBI shRNA silencing AAV

Name
AAV-h-BAMBI-shRNA

Cat No
shAAV-201955

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human BAMBI.

shAAV-201955

AAV-h-BAMBI-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BAMBI (BMP and activin membrane bound inhibitor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

NMA

Description (Vector)

BAMBI encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis.

Gene ID

25805

Gene Name (Vector)

BMP and activin membrane bound inhibitor

Gene Symbol

BAMBI

HGNC ID

HGNC:30251

ORF Size (aa)

783

ORF Size (bp)

783 bp

RefSeq ID

NM_012342

RefSeq Synonyms

NM_012342, BC019252,

Species

human

UniGene ID

Hs.533336

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.