human AVPR1B shRNA silencing AAV

Name 
AAV-h-AVPR1B-shRNA
Cat No 
shAAV-201848
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human AVPR1B.

shAAV-201848
AAV-h-AVPR1B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AVPR1B (arginine vasopressin receptor 1B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AVPR3
Description (Vector)
AVPR1B acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.
Gene ID
553
Gene Name (Vector)
arginine vasopressin receptor 1B
Gene Symbol
AVPR1B
HGNC ID
HGNC:896
ORF Size (aa)
1272
ORF Size (bp)
1272 bp
RefSeq ID
NM_000707
RefSeq Synonyms
NM_000707, BC157126, BC156078,
Species
human
UniGene ID
Hs.1372

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.