human AVPR1A shRNA silencing AAV

Name
AAV-h-AVPR1A-shRNA

Cat No
shAAV-201845

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human AVPR1A.

shAAV-201845

AAV-h-AVPR1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AVPR1A (arginine vasopressin receptor 1A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AVPR V1a; AVPR1; V1aR

Description (Vector)

AVPR1A acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis.

Gene ID

552

Gene Name (Vector)

arginine vasopressin receptor 1A

Gene Symbol

AVPR1A

HGNC ID

HGNC:895

ORF Size (aa)

1257

ORF Size (bp)

1257 bp

RefSeq ID

NM_000706

RefSeq Synonyms

NM_000706, BC074804, BC074803,

Species

human

UniGene ID

Hs.2131

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.