human ATP6V1G1 shRNA silencing AAV

Cat. No: shAAV-201771

Availability: 4-5 weeks

Name: AAV-h-ATP6V1G1-shRNA

This is an AAV expressing shRNA for silencing of Human ATP6V1G1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ATP6V1G1
Gene Name: ATPase H+ transporting V1 subunit G1
Gene ID: 9550
Gene Synonyms: ATP6G; ATP6G1; ATP6GL; ATP6J; Vma10
ORF Size: 357 bp
RefSeq#: NM_004888
Gene Description: ATP6V1G1 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of three V1 domain G subunit proteins. Pseudogenes of this gene have been characterized.
UniGene ID: Hs.388654
HGNC ID: HGNC:864