human ATP6V0A2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ATP6V0A2.
shAAV-201743
AAV-h-ATP6V0A2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ATP6V0A2 (ATPase H+ transporting V0 subunit a2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A2; ARCL; ARCL2A; ATP6A2; ATP6N1D; J6B7; RTF; STV1; TJ6; TJ6M; TJ6S; VPH1; WSS
Description (Vector)
ATP6V0A2 is a subunit of the vacuolar ATPase (v-ATPase), an heteromultimeric enzyme that is present in intracellular vesicles and in the plasma membrane of specialized cells, and which is essential for the acidification of diverse cellular components. V-ATPase is comprised of a membrane peripheral V(1) domain for ATP hydrolysis, and an integral membrane V(0) domain for proton translocation. The subunit encoded by this gene is a component of the V(0) domain. Mutations in this gene are a cause of both cutis laxa type II and wrinkly skin syndrome.
Gene ID
23545
Gene Name (Vector)
ATPase H+ transporting V0 subunit a2
Gene Symbol
ATP6V0A2
HGNC ID
HGNC:18481
ORF Size (aa)
2571
ORF Size (bp)
2571 bp
RefSeq ID
NM_012463
RefSeq Synonyms
NM_012463, BC068531,
Species
human
UniGene ID
Hs.201939
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.