human ATOH7 shRNA silencing AAV

Name
AAV-h-ATOH7-shRNA

Cat No
shAAV-201661

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ATOH7.

shAAV-201661

AAV-h-ATOH7-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ATOH7 (atonal bHLH transcription factor 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

bHLHa13; Math5; NCRNA; PHPVAR; RNANC

Description (Vector)

This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment.

Gene ID

220202

Gene Name (Vector)

atonal bHLH transcription factor 7

Gene Symbol

ATOH7

HGNC ID

HGNC:13907

ORF Size (aa)

459

RefSeq ID

NM_145178

RefSeq Synonyms

NM_145178, BC032621,

Species

human

UniGene ID

Hs.175396

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.