human ATG9B shRNA silencing AAV

Name 
AAV-h-ATG9B-shRNA
Cat No 
shAAV-201648
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ATG9B.

shAAV-201648
AAV-h-ATG9B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ATG9B (ATG9 autophagy related 9 homolog B (S. cerevisiae)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
APG9L2; NOS3AS; SONE;
Description (Vector)
ATG9B functions in the regulation of autophagy, a lysosomal degradation pathway. ATG9B also functions as the antisense to and in the posttranscriptional regulation of endothelial nitric oxide synthase 3. Mutations in this gene and disruption of the autophagy process have been associated with multiple cancers. Transcript evidence indicates this is a nonsense-mediated decay (NMD) candidate; however, published reports support a valid protein.
Gene ID
285973
Gene Name (Vector)
ATG9 autophagy related 9 homolog B (S. cerevisiae)
Gene Symbol
ATG9B
HGNC ID
HGNC:21899
ORF Size (aa)
1233
ORF Size (bp)
1233 bp
RefSeq ID
NM_173681
RefSeq Synonyms
NM_173681, NM_001317056, BC128587,
Species
human
UniGene ID
Hs.707300

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.