human ATG12 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ATG12.
shAAV-201633
AAV-h-ATG12-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ATG12 (autophagy related 12). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
APG12; APG12L; FBR93; HAPG12
Description (Vector)
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 (PubMed 9852036)).(supplied by OMIM, Mar 2008)
Gene ID
9140
Gene Name (Vector)
autophagy related 12
Gene Symbol
ATG12
HGNC ID
HGNC:588
ORF Size (aa)
564
ORF Size (bp)
564 bp
RefSeq ID
NM_004707
RefSeq Synonyms
NM_004707, NM_001277783, BC012266,
Species
human
UniGene ID
Hs.264482
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.