human ATF7 shRNA silencing AAV

Name 
AAV-h-ATF7-shRNA
Cat No 
shAAV-201628
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ATF7.

shAAV-201628
AAV-h-ATF7-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ATF7 (activating transcription factor 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Activating transcription factor 7; ATFA; cAMP-dependent transcription factor ATF-7; cyclic AMP-dependent transcription factor ATF-7; transcription factor ATF-A
Description (eCommerce)
Activating transcription factor 7 (ATF7) is homologous to ATF2. ATF7 was identified as a protein that interacts with the PRL-1 protein-tyrosine phosphatase. It is a basic leucine zipper (bZIP) and C2H2- type zinc-finger containing transcription factor that binds to consensus cAMP response elements (CRE). ATF7 interacts with TAF12, a subunit of the TFIID general transcription factor, to promote transcription.
Gene ID
11016
Gene Name (eCommerce)
activating transcription factor 7
Gene Name (Vector)
activating transcription factor 7
Gene Symbol
ATF7
HGNC ID
HGNC:792
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1452
ORF Size (bp)
1452 bp
Protein Name (eCommerce)
Cyclic AMP-dependent transcription factor ATF-7
RefSeq ID
NM_006856
RefSeq Synonyms
NM_006856, NM_001206683, NM_001206682, NM_001130060, NM_001130059, BC136302,
Research Areas
Host-Virus Interactions,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,infectious_disease,transcription_translation
Species
human
Target Sentence
Activating transcription factor 7 (ATF7) is homologous to ATF2. ATF7 was identified as a protein that interacts with the PRL-1 protein-tyrosine phosphatase. It is a basic leucine zipper (bZIP) and C2H2- type zinc-finger containing transcription factor that binds to consensus cAMP response elements (CRE). ATF7 interacts with TAF12, a subunit of the TFIID general transcription factor, to promote transcription.
UniGene ID
Hs.633602
UniProt ID (eCommerce)
P17544

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.