human ASAH2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ASAH2.
shAAV-201507
AAV-h-ASAH2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ASAH2 (N-acylsphingosine amidohydrolase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BCDase; HNAC1; LCDase; N-CDase; NCDase
Description (Vector)
Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 (PubMed 11328816)).(supplied by OMIM, Mar 2008)
Gene ID
56624
Gene Name (Vector)
N-acylsphingosine amidohydrolase 2
Gene Symbol
ASAH2
HGNC ID
HGNC:18860
ORF Size (aa)
2181
ORF Size (bp)
2181 bp
RefSeq ID
NM_019893
RefSeq Synonyms
NM_019893, NM_001143974, BC107105,
Species
human
UniGene ID
Hs.512645
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.