human ART4 shRNA silencing AAV

Name 
AAV-h-ART4-shRNA
Cat No 
shAAV-201501
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ART4.

shAAV-201501
AAV-h-ART4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ART4 (ADP-ribosyltransferase 4 (Dombrock blood group)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ARTC4; CD297; DO; DOK1
Description (Vector)
ART4 encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. Antigens of the Dombrock blood group system are located on the gene product, which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane. Allelic variants, some of which lead to adverse transfusion reactions, are known.
Gene ID
420
Gene Name (Vector)
ADP-ribosyltransferase 4 (Dombrock blood group)
Gene Symbol
ART4
HGNC ID
HGNC:726
ORF Size (aa)
945
ORF Size (bp)
945 bp
RefSeq ID
NM_021071
RefSeq Synonyms
NM_021071, BC074727,
Species
human
UniGene ID
Hs.668803

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.