human ARPC1A shRNA silencing AAV

Name
AAV-h-ARPC1A-shRNA

Cat No
shAAV-201457

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ARPC1A.

shAAV-201457

AAV-h-ARPC1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ARPC1A (actin related protein 2/3 complex subunit 1A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Arc40; HEL-68; HEL-S-307; SOP2Hs; SOP2L

Description (Vector)

ARPC1A encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID

10552

Gene Name (Vector)

actin related protein 2/3 complex subunit 1A

Gene Symbol

ARPC1A

HGNC ID

HGNC:703

ORF Size (aa)

1113

ORF Size (bp)

1113 bp

RefSeq ID

NM_006409

RefSeq Synonyms

NM_006409, NM_001190996, BC054027, BC047889, BC039594,

Species

human

UniGene ID

Hs.124126

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.