human ARHGDIA shRNA silencing AAV

Name 
AAV-h-ARHGDIA-shRNA
Cat No 
shAAV-201338
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ARHGDIA.

shAAV-201338
AAV-h-ARHGDIA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ARHGDIA (Rho GDP dissociation inhibitor alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GDIA1; HEL-S-47e; NPHS8; RHOGDI; RHOGDI-1
Description (Vector)
Aplysia Ras-related homologs (ARHs), also called Rho genes, belong to the RAS gene superfamily encoding small guanine nucleotide exchange (GTP/GDP) factors. The ARH proteins may be kept in the inactive, GDP-bound state by interaction with GDP dissociation inhibitors, such as ARHGDIA (Leffers et al., 1993 (PubMed 8262133)).(supplied by OMIM, Jan 2009)
Gene ID
396
Gene Name (Vector)
Rho GDP dissociation inhibitor alpha
Gene Symbol
ARHGDIA
HGNC ID
HGNC:678
ORF Size (aa)
615
ORF Size (bp)
615 bp
RefSeq ID
NM_004309
RefSeq Synonyms
NM_004309, NM_001301243, NM_001301242, NM_001301241, NM_001301240, NM_001185078, NM_001185077, BC106044, BC075827, BC027730, BC024258, BC016185, BC016031, BC009759, BC008701, BC005875, BC005851,
Species
human
UniGene ID
Hs.159161

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.