human ARF3 shRNA silencing AAV

Name
AAV-h-ARF3-shRNA

Cat No
shAAV-201268

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ARF3.

shAAV-201268

AAV-h-ARF3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ARF3 (ADP ribosylation factor 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

ADP-ribosylation factor 3 (ARF3) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization. The ARF3 gene contains five exons and four introns.

Gene ID

377

Gene Name (Vector)

ADP ribosylation factor 3

Gene Symbol

ARF3

HGNC ID

HGNC:654

ORF Size (aa)

546

ORF Size (bp)

546 bp

RefSeq ID

NM_001659

RefSeq Synonyms

NM_001659, BC028402, BC017565, BC007762, BC007647,

Species

human

UniGene ID

Hs.715625

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.